Pathological and immunological observations on tropical spastic paraparesis in patients from Jamaica.

P Piccardo,M Ceroni,P Rodgers-Johnson,C Mora,D M Asher,G Char,C J Gibbs,D C Gajdusek

ANNALS OF NEUROLOGY（1988）

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摘要

The neuropathological examination of the spinal cord of 2 Jamaican patients with classical tropical spastic paraparesis disclosed an intense chronic meningomyelitis with demyelination. In the 1 case in which serum and cerebrospinal fluid were available, antibodies to the human T-lymphotropic virus type 1 were found.

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