Short-term hypertension is associated with the development of atrial fibrillation substrate: A study in an ovine hypertensive model

Dennis H. Lau,Lorraine Mackenzie,Darren J. Kelly,Peter J. Psaltis,Michael Worthington,Arumuga Rajendram,Douglas R. Kelly,Adam J. Nelson,Yuan Zhang,Pawel Kuklik,Anthony G. Brooks,Stephen G. Worthley,Randall J. Faull,Mohan Rao,James Edwards,David A. Saint,Prashanthan Sanders

Heart Rhythm（2010）

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摘要

Conclusion Short-duration hypertension is associated with significant atrial remodeling characterized by atrial enlargement/dysfunction, interstitial fibrosis, inflammation, slowed/heterogeneous conduction, increased ERP, and greater propensity for AF.

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关键词

Hypertension,Arrhythmia,Atria,Remodeling,Magnetic resonance imaging

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