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Substituted Tetrahydroquinolines As Potent Allosteric Inhibitors of Reverse Transcriptase and Its Key Mutants.

Dai-Shi Su,John J. Lim,Elizabeth Tinney,Bang-Lin Wan,Mary Beth Young,Kenneth D. Anderson,Deanne Rudd,Vandna Munshi,Carolyn Bahnck,Peter J. Felock,Meiqing Lu,Ming-Tain Lai,Sinoeun Touch,Gregory Moyer,Daniel J. DiStefano,Jessica A. Flynn,Yuexia Liang,Rosa Sanchez,Sridhar Prasad,Youwei Yan,Rebecca Perlow-Poehnelt,Maricel Torrent,Mike Miller,Joe P. Vacca,Theresa M. Williams,Neville J. Anthony

Bioorganic & Medicinal Chemistry Letters（2009）

Cited 38|Views76
Key words
Non-nucleoside reverse transcriptase inhibitor (NNRTI),SAR,Molecular modeling,Crystal structure,Mutant virus,Tetrahydroquinoline
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