Efficacy, safety and pharmacokinetics of 900/100 mg of darunavir/ritonavir once daily in treatment-experienced patients.

Adrian Curran,Mar Gutirerrez,Elisabet Deig,Gracia Mateo,Rosa Maria Lopez,Arkaitz Imaz,Manuel Crespo,Inma Ocaña,Pere Domingo,Esteban Ribera

Journal of Antimicrobial Chemotherapy（2010）

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摘要

Darunavir/ritonavir at 900/100 mg once daily is highly effective, safe and well tolerated in treatment-experienced patients with no darunavir resistance, both in early salvage and switch strategies. Adequate drug plasma levels were achieved in all patients.

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关键词

HIV infection,antiretroviral treatment,switch strategies,early salvage,drug plasma levels

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