Pyrrolidinedione derivatives as antibacterial agents with a novel mode of action.

Jens Pohlmann,Thomas Lampe,Mitsuyuki Shimada,Peter G Nell,Josef Pernerstorfer,Niels Svenstrup,Nina A Brunner,Guido Schiffer,Christoph Freiberg

Bioorganic & Medicinal Chemistry Letters（2005）

引用 95|浏览22

暂无评分

摘要

Pyrrolidinediones represent a new class of antibiotics that target bacterial fatty acid biosynthesis. Structure–activity relationships for the pyrrolidinedione group and the fatty acid side chain are described.

查看译文

关键词

Pyrrolidine diones,Moiramide B,Andrimid,Acetyl-CoA carboxylase,Antibiotic

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要