Genetic variations in HLA-B region and hypersensitivity reactions to abacavir
Lancet (London, England), Volume 359, Issue 9312, 2002, Pages 1121-1122.
Hypersensitivity to abacavir affects about 4% of patients who receive the drug for HIV-1 infection. We did a retrospective, case-control study to identify multiple markers in the vicinity of HLA-B associated with hypersensitivity reactions. HLA-B57 was present in 39 (46%) of 84 patients versus four (4%) of 113 controls (p<0 small middle d...More
Full Text (Upload PDF)
PPT (Upload PPT)