Altered EGFR localization and degradation in human breast cancer cells with an amphiregulin/EGFR autocrine loop
Cellular Signalling, pp. 212-219, 2009.
The epidermal growth factor receptor (EGFR) and its ligand amphiregulin (AR) have been shown to be co-over expressed in breast cancer. We have previously shown that an AR/EGFR autocrine loop is required for SUM149 human breast cancer cell proliferation, motility and invasion. We also demonstrated that AR can induce these altered phenotype...More
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