Detection of Azithromycin Resistance in Treponema pallidum by Real-Time PCR

Mark W. Pandori, Charmie Gordones,Lina Castro,Joseph Engelman,Mark Siedner,Sheila Lukehart,Jeffrey Klausner

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY（2007）

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摘要

We describe a real-time PCR assay for the discrimination of azithromycin-resistant and -susceptible strains of Treponema pallidum. This assay is rapid and allows for as many as 30 clinical specimens to be analyzed simultaneously without the need for DNA sequencing.

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