BNIP3 protects HepG2 cells against etoposide-induced cell death under hypoxia by an autophagy-independent pathway.
Biochemical Pharmacology(2010)
摘要
Etoposide induces cell death through both apoptosis and autophagy. Hypoxia prevents cell death by inhibiting apoptosis in a BNIP3-dependent way without interfering with autophagy.
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关键词
Apoptosis,Autophagy,BNIP3,Hypoxia,Cancer cells
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