Prolactin modulates survival and cellular immune functions in septic mice11This study was supported by a grant from the Else-Kröner Fresenius Stiftung.

Reiner Oberbeck,Daniel Schmitz,Klaus Wilsenack,Mark Schüler,Claudia Biskup,Manfred Schedlowski,Dieter Nast-Kolb,Michael S Exton

Journal of Surgical Research（2003）

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摘要

Conclusions We conclude that prolactin has profound immunomodulatory properties and that administration of prolactin in pharmacological doses is associated with a decreased survival and an inhibition of cellular immune functions in septic mice.

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prolactin,immune function,sepsis,immune-endocrine interaction

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