A conformationally constrained inhibitor with an enhanced potency for β-tryptase and stability against semicarbazide-sensitive amine oxidase (SSAO).
Bioorganic & Medicinal Chemistry Letters（2010）
摘要
Conformationally constrained β-tryptase inhibitor.
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关键词
Tryptase,Inhibitor,Molecular modeling,Structure-based drug design,X-ray,Benzylamine,SSAO
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