Multicomponent Approach For The Synthesis Of Phenanthridine And Acridine Ring Systems Via The Coupling Of Fischer Carbene Complexes With Heteroaromatic O-Alkynyl Carbonyl Derivatives

A one-pot multicomponent synthesis of phenanthridine and acridine derivatives is described. This method includes the in situ generation of furo[3,4-c]isoquinoline and furo[3,4-b]quinoline intermediates by the coupling of heteroaromatic o-alkynyl carbonyl derivatives with Fischer carbene complexes and subsequent trapping of these intermediates by suitable dienophiles.