BCL9-2 Promotes Early Stages of Intestinal Tumor Progression

Felix H. Brembeck,Maria Wiese,Nathalie Zatula,Tamara Grigoryan,Yiyang Dai,Johannes Fritzmann,Walter Birchmeier

Gastroenterology（2011）

引用 52|浏览36

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摘要

Discussion BCL9-2 promotes early phases of intestinal tumor progression in humans and in transgenic mice. BCL9-2 increases the expression of a subset of canonical Wnt target genes, but also regulates genes that are required for early stages of tumor progression.

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关键词

Colon Cancer,Carcinogenesis,Mouse Model

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