Synthesis and structure determination of some oxadiazole-2-thione and triazole-3-thione galactosides.

The syntheses of 5-pyridyl-3(beta -D-galactopyranosyl)-1,3,4-oxadiazole-2-thiones 3a-3c and 5-pyridyl-2(beta -D-galactopyranosyl)-4-benzyl-1,2, 4-triazole-3-thiones 6a-6c are reported. The existence of N-galactosides - not S-galactosides - was proven by IR and N-15 NMR spectroscopy. The structures of the final products and the intermediates were elucidated by IR, H-1, C-13 and N-15 NMR spectroscopy and mass spectrometry.