A robust immunoassay for anti-interferon autoantibodies that is highly specific for patients with autoimmune polyglandular syndrome type 1

Clinical immunology (Orlando, Fla.), Volume 125, Issue 2, 2007, Pages 131-137.

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Keywords:
autoantibodiesstandard deviationhigh throughputindexation

Abstract:

High titer antibodies to type 1 interferons have been recently reported as being highly specific for patients with autoimmune polyglandular syndrome type 1 (APS1) in Finnish and Norwegian patients with mutations in the AIRE gene. Those studies employed a complex neutralization assay to define the type 1 interferon autoantibodies. Here we ...More

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