Système cardiovasculaire du sujet âgé normal. Sénescence cardiovasculaire
Comptes Rendus Biologies(2008)
摘要
The cardiovascular system of the elderly is characterised by (i) an increased characteristic impedance of the big vessels, without hypertension; (ii) a cardiac index unchanged at rest and during submaximal exercising, despite a diminished VO2max; (iii) a diastolic dysfunction with reduced rapid early filling (E wave at echo) and enhanced atrial systole (A wave); (iv) benign arrhythmias; (v) a reduced coronary reserve and an increased sensitivity to ischemia; (vi) an efficacy of converting enzyme inhibitors remaining unchanged, despite an altered renin–agiotensin system.
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关键词
senescence,cardiovascular system,physiology,aortic impedance,arrhythmias,coronary ischemia,renin–angiotensin system,converting enzyme inhibitors
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