Système cardiovasculaire du sujet âgé normal. Sénescence cardiovasculaire

Comptes Rendus Biologies(2008)

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摘要
The cardiovascular system of the elderly is characterised by (i) an increased characteristic impedance of the big vessels, without hypertension; (ii) a cardiac index unchanged at rest and during submaximal exercising, despite a diminished VO2max; (iii) a diastolic dysfunction with reduced rapid early filling (E wave at echo) and enhanced atrial systole (A wave); (iv) benign arrhythmias; (v) a reduced coronary reserve and an increased sensitivity to ischemia; (vi) an efficacy of converting enzyme inhibitors remaining unchanged, despite an altered renin–agiotensin system.
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关键词
senescence,cardiovascular system,physiology,aortic impedance,arrhythmias,coronary ischemia,renin–angiotensin system,converting enzyme inhibitors
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