PS212. Human Adult Stem Cells Restore Endothelial Migratory Dysfunction in a Hypoxic Environment

Sarah Fernandez,Rachel Song,Jason Comeau,Stephen McIlhenny,Ping Zhang,Hamid Abdollahi,Thomas Tulenko,Paul DiMuzio

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY（2010）

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摘要

Adipose-derived stem cells (ASCs) injected into the blood stream after an ischemic event promote therapeutic angiogenesis in affected tissues. It has been suggested that the stem cells exert their influence by way of a paracrine effect on native endothelial cells (ECs). Using an in vitro model, we evaluated the effect of ASC coculture on EC function in a hypoxic environment.

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adult stem cell

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