Fatty acid amide hydrolase inhibitors. Surprising selectivity of chiral azetidine ureas.

Bioorganic & Medicinal Chemistry Letters（2009）

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摘要

We report the discovery of a novel, chiral azetidine urea inhibitor of Fatty Acid Amide Hydrolase (FAAH,) and describe the surprising species selectivity of VER-156084 versus rat and human FAAH and also hCB1.

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关键词

FAAH, fatty acid amide hydrolase,Azetidine,Urea,Inhibitor

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