Chemokine receptors in advanced breast cancer: differential expression in metastatic disease sites with diagnostic and therapeutic implications.

N Cabioglu,A A Sahin,P Morandi, F Meric-Bernstam,R Islam,H Y Lin,C D Bucana,A M Gonzalez-Angulo, G N Hortobagyi,M Cristofanilli

Annals of Oncology（2009）

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摘要

Background: We investigated the expression of CXCR4, CCR7, estrogen receptor (ER), progesterone receptor (PR) and HER2-neu in human metastatic breast cancers to determine whether these biological biomarkers were preferentially expressed in any organ-specific metastases.

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bone metastases,CCR7,CXCR4,HER2-neu,metastatic breast cancer

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