Candida endophthalmitis: A complication of prolonged intravenous therapy and antibiotic treatment

Four patients with candida endophthalmitis are discussed; three had received prolonged intravenous therapy as well as multiple and varied courses of antibiotics for underlying gastro-intestinal disease; one was an intravenous drug abuser. The visual acuity improved dramatically in two of the five affected eyes but in the remaining three eyes remained at 6/60 or less. Visual prognosis is directly related to early diagnosis and treatment, which should include pars plana vitrectomy and systemic antifungal therapy.