Workshop: Algorithms for discovery of mutated pathways in cancer

    ICCABS, pp. 1-1, 2012.

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    Keywords:
    Markov processesMonte Carlo methodsadhesioncancercellular biophysicsMore(20+)

    Abstract:

    We apply our algorithms to several cancer types including glioblastoma multiforme (GBM), lung adenocarcinoma, and ovarian carcinoma (OV). HotNet identifies significant subnetworks that are part of well-known cancer pathways as well as novel subnetworks. Among the most significant subnetworks identified in OV data is the Notch signaling pa...More

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