Drug-Induced Maculopathy

International ophthalmology clinics(2020)

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摘要
Purpose of reviewThe purpose of this article is to provide an overview of drug-induced maculopathies including their clinical presentations, diagnostic findings, and treatment options. With the increasing pace of development and arrival of drugs to the market, this review aims to inform retina specialists of relevant side effects that may be encountered in a clinical practice setting.Recent findingsThe major themes visited in this article focus on relevant findings of drugs that cause pigmentary and crystalline maculopathy, photoreceptor dysfunction, cystoid macular edema, central serous choroidopathy, uveitis, and vascular damage.SummaryThe current review reports updated findings and discusses the pathophysiologic mechanisms, presentations, and treatments of drug-induced maculopathies.
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关键词
BRAF inhibitor, checkpoint inhibitor, crystalline, maculopathy, medication, mitogen-activated protein kinase kinase inhibitor, pentosan, Plaquenil, retinopathy, toxicity
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