Dendritic skin cells

Sueli Coelho Carneiro,Raphael Medeiros, Marcelo Alves Brollo,Marcia Ramos-e-Silva,Mirian Nacagami Sotto

Expert Review of Dermatology（2014）

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摘要

Dendritic cells (DCs) are the most potent antigen-presenting cells of the immune system. To become potent T-cell stimulators, DCs have to mature. Immature DCs reside in peripheral tissues. With antigen uptake and exposure to infl ammatory stimuli, they migrate to peripheral lymph nodes where, as mature DCs, they express additional molecules that can induce T-cell stimulation.

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