Beyond Identity- When Classical Homology Searching Fails, Why, and What you Can do About It

William C. Ray,Hatice G. Ozer,David W. Armbruster,Charles J. Daniels

Cleveland, OH（2009）

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摘要

In this paper we report an ongoing project for identifying human cytomegalovirus (HCMV) micro RNAs (miRNA) expressed in infected human cells using the new massive parallel sequencing technology with the Solexa Sequencer. We developed a data processing ...

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关键词

infected human cell,micro rnas,solexa sequencer,ongoing project,data processing,beyond identity,massive parallel sequencing technology,human cytomegalovirus,classical homology searching,organisms,data mining,pediatrics,modeling,genome sequence,hidden markov models,multiple sequence alignment,bioinformatics,genomics,homology modeling,ribosomal rna,visualization,biochemistry,proteins,hidden markov model,homology,collaboration,molecular biophysics,rna,markov processes,biomedical informatics,bismuth

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