An algorithm for clustering cDNAs for gene expression analysis

RECOMB '99: Proceedings of the third annual international conference on Computational molecular biology(1999)

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摘要
We have developed a novel algorithm for cluster analysisthat is based on graph theoretic techniques. A similaritygraph is defined and clusters in that graph correspond tohighly connected subgraphs. A polynomial algorithm tocompute them efficiently is presented. Our algorithm producesa clustering with some provably good properties.The application that motivated this study was gene expressionanalysis, where a collection of cDNAs must be clusteredbased on their oligonucleotide...
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关键词
gene expression analysis,clustering cdnas,computational biology,branch and cut
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