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职业迁徙
个人简介
Current Research Interests
More than 99% of biomedical researchers study only around 2% of the human genome, occupied by regular genes. By contrast, the ZZ-Lab is fascinated with the genomic content taking half of our genome–the jumping gene, also known as transposon. Besides their abundance, transposons represent a potentially explosive source of genomic instability that can cause animal sterility and disease (such as cancer), and potentially drive aging. We aim to uncover how transposons are controlled and their influence on reproduction, development, and disease. We also aim to harness transposons to develop personalized cancer vaccines. Our projects are multidisciplinary in nature and involve genetics, genomics, cell biology, cutting-edge imaging and sequencing technologies, and computational biology.
More than 99% of biomedical researchers study only around 2% of the human genome, occupied by regular genes. By contrast, the ZZ-Lab is fascinated with the genomic content taking half of our genome–the jumping gene, also known as transposon. Besides their abundance, transposons represent a potentially explosive source of genomic instability that can cause animal sterility and disease (such as cancer), and potentially drive aging. We aim to uncover how transposons are controlled and their influence on reproduction, development, and disease. We also aim to harness transposons to develop personalized cancer vaccines. Our projects are multidisciplinary in nature and involve genetics, genomics, cell biology, cutting-edge imaging and sequencing technologies, and computational biology.
研究兴趣
论文共 10 篇作者统计合作学者相似作者
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Yaosi Liang,Christopher Pan, Tao Yin,Lu Wang, Xia Gao,Ergang Wang, Holly Quang,De Huang, Lianmei Tan, Kun Xiang,Yu Wang,Peter B. Alexander,
ADVANCED SCIENCEno. 2 (2024): e2303489-e2303489
Natureno. 7972 (2023): 218-225
biorxiv(2022)
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