Zhen Chen

Departments of Bioengineering and Medicine and Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093

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Endothelial mechanobiology

Ming He, Marcy Martin, Traci Marin,Zhen Chen, Brendan Gongol

APL bioengineering, no. 1 (2020): 010904

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Genome-wide colocalization of RNA-DNA interactions and fusion RNA pairs

Zhangming Yan, Norman Huang, Weixin Wu,Weizhong Chen, Yiqun Jiang, Jingyao Chen, Xuerui Huang, Xingzhao Wen,Jie Xu, Qiushi Jin,Kang Zhang,Zhen Chen

Proceedings of the National Academy of Sciences of the United States of America, no. 8 (2019): 201819788-3337

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Atheroprotective Flow Upregulates ITPR3 (Inositol 1,4,5-Trisphosphate Receptor 3) in Vascular Endothelium via KLF4 (Krüppel-Like Factor 4)-Mediated Histone Modifications

Ming He, Tse-Shun Huang, Shuai Li, Hsiao-Chin Hong,Zhen Chen,Marcy Martin, Xin Zhou,Hsi-Yuan Huang, Shu-Han Su, Jiao Zhang, Wei-Ting Wang, Jian Kang

Arteriosclerosis, thrombosis, and vascular biology, no. 5 (2019): 902-914

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Extracellular MicroRNA-92a Mediates Endothelial Cell-Macrophage Communication

Ya-Ju Chang,Yi-Shuan Li,Chia-Ching Wu,Kuei-Chun Wang, Tzu-Chieh Huang,Zhen Chen,Shu Chien

Arteriosclerosis, thrombosis, and vascular biology, (2019)

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AMPK Phosphorylation of ACE2 in Endothelium Mitigates Pulmonary Hypertension

Jiao Zhang, Jianjie Dong,Marcy Martin,Ming He,Brendan Gongol,Traci L Marin, Lili Chen, Xinxing Shi, Yanjun Yin, Fenqing Shang,Yan Wu, Hsi-Yuan Huang

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, no. 4.0 (2018): 509-520

Cited by4WOSBibtex

Epigenetic profiling with ultralow DNA amounts

Feng-Mao Lin,Shu Chien,Zhen Chen

Nature Biomedical Engineering, no. 3 (2018): 146-147

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Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function

Yifei Miao, Nassim E Ajami, Tse-Shun Huang, Feng-Mao Lin, Chih-Hong Lou, Yun-Ting Wang, Shuai Li,Jian Kang, Hannah Munkacsi,Mano R Maurya,Shakti Gupta,Shu Chien

Nature communications, no. 1 (2018): 292

Cited by16WOSBibtex

Abstract 685: Sterol Regulatory Element-Binding Protein 2-Mediated Endothelial-to-Mesenchymal Transition Contributes to Pulmonary Fibrosis

Marcy Martin, Jiao Zhang, Yifei Miao, Jian Kang, Hsi-Yuan Huang,Ming He, Jianjie Dong,Simon Wong,Hsien-Da Huang,Zhen Chen,James S Hagood,John Y Shyy

Arteriosclerosis, Thrombosis, and Vascular Biology, (2018)

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Abstract 250: Endothelial functional Regulation by Enhancer-Associated Long Non-Coding RNAs

Zhen Chen, Yifei Miao, Feng-Mao Lin

Arteriosclerosis, Thrombosis, and Vascular Biology, (2018)

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T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice

Wen Liu,Wenjie Guo, Lihong Shen,Zhen Chen,Qiong Luo,Xiaolin Luo,GenSheng Feng,Yongqian Shu,Yanhong Gu,Qiang Xu,Yang Sun

Oncotarget, no. 5 (2017): 7586-7597

Cited by4WOSBibtex

LINC00341 exerts an anti-inflammatory effect on endothelial cells by repressing VCAM1

Tse-Shun Huang,Kuei-Chun Wang, Sara Quon,Phu Nguyen, Ting-Yu Chang,Zhen Chen,Yi-Shuan Li,Shankar Subramaniam,John Shyy,Shu Chien

Physiological genomics, no. 7 (2017): 339-345

Cited by13WOSBibtex

Epigenetic Regulation: A New Frontier for Biomedical Engineers

Zhen Chen, Shuai Li,Shankar Subramaniam,John Y-J Shyy,Shu Chien

ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 19, (2017): 195-219

Cited by17WOSBibtex

miR-483 Targeting of CTGF Suppresses Endothelial-to-Mesenchymal Transition: Therapeutic Implications in Kawasaki Disease

Ming He,Zhen Chen,Marcy Martin,Jin Zhang, Panjamaporn Sangwung,Brian Woo,Adriana H. Tremoulet,Adriana H. Tremoulet,Chisato Shimizu,Mukesh K. Jain,Jane C. Burns,Jane C. Burns

Circulation Research, no. 2 (2017): 354-365

Cited by22Bibtex

Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis

Wenjie Guo,Wen Liu,Zhen Chen,Yanhong Gu, Shuang Peng, Lihong Shen,Yan Shen,Xingqi Wang,Gen-Sheng Feng,Yang Sun,Qiang Xu

Nature communications, no. 1 (2017): 2168-2168

Cited by8WOSBibtex

Systems biology analysis of longitudinal functional response of endothelial cells to shear stress

Nassim E Ajami,Shakti Gupta,Mano R Maurya,Phu Nguyen,Julie Yi-Shuan Li,John Y-J Shyy,Zhen Chen,Shu Chien,Shankar Subramaniam

Proceedings of the National Academy of Sciences of the United States of America, no. 41 (2017)

Cited by8WOSBibtex

miR-483 Targeting of CTGF Suppresses Endothelial-to-Mesenchymal Transition

Ming He,Zhen Chen,Marcy Martin,Jin Zhang, Panjamaporn Sangwung,Brian Woo,Adriana H. Tremoulet,Chisato Shimizu,Mukesh K. Jain,Jane C. Burns,John Y.-J. Shyy

Circulation Research, (2017)

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MicroRNA-92a Mediates Endothelial Dysfunction in CKD

Fenqing Shang,Shen-Chih Wang,Chien-Yi Hsu, Yifei Miao,Marcy Martin, Yanjun Yin,Chih-Cheng Wu, Yun-Ting Wang, Gaihong Wu,Shu Chien,Hsien-Da Huang, Der-Cherng Tarng

Journal of the American Society of Nephrology : JASN, (2017)

Cited by9WOSBibtex

Abstract 15912: MicroRNA-92a Mediates Endothelial Dysfunction in Chronic Kidney Disease

Fenqing Shang,Shen-Chih Wang, Chien-Yi Hsu,Yan-Ting E Shiu,Po-Hsun Huang,John Y.-J. Shyy,Zhen Chen

Circulation, (2016)

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TIFA as a crucial mediator for NLRP3 inflammasome

Ting-Yang Lin,Tong-You Wade Wei, Shuai Li,Shen-Chih Wang,Ming He, Marcy Martin, Jiao Zhang,Tzu-Pin Shentu,Han Xiao, Jian Kang,Kuei-Chun Wang,Zhen Chen

Proceedings of the National Academy of Sciences of the United States of America, no. 52 (2016): 15078-15083

Cited by7WOSBibtex

Cardiovascular Protective Effect of Metformin and Telmisartan: Reduction of PARP1 Activity via the AMPK-PARP1 Cascade

Fenqing Shang, Jiao Zhang,Zhao Li,Jin Zhang, Yanjun Yin, Yaqiong Wang,Traci Marin,Brendan Gongol,Han Xiao,Youyi Zhang,Zhen Chen,John Y.-J. Shyy

PLOS ONE, no. 3 (2016)

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