From 2006-2011, Yvonne was professor of HCI in the Computing Department at the Open University, where she set up the Pervasive Interaction Lab. From 2003-2006, she was a professor in Informatics at Indiana University. Prior to this, she spent 11 years at the former School of Cognitive and Computing Sciences at Sussex University. She has spent sabbaticals at Stanford, Apple, Queensland University, University of Cape Town, University of Melbourne, QUT and UC San Diego.
Yvonne was one of the principal investigators on the UK Equator Project (2000-2007) where she pioneered ubiquitous learning. She has published widely, beginning with her PhD work on graphical interfaces to her recent work on public visualisations and behavioural change. She is one of the authors of the definitive textbook on Interaction Design and HCI (4th edition just out), that has sold over 150,000 copies worldwide and has been translated into 6 languages. She is a Fellow of the British Computer Society and the ACM's CHI Academy: "an honorary group of individuals who have made substantial contributions to the field of human-computer interaction. These are the principal leaders of the field, whose efforts have shaped the disciplines and/or industry, and led the research and/or innovation in human-computer interaction."