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职业迁徙
个人简介
My enthusiasm for research draws from my interest in the biochemistry and physiology of nutrition-related diseases and in targeted and population-based strategies of chronic disease prevention and optimal health promotion. My research focuses on micronutrients and specifically B-vitamins and their kinetics and functions in human metabolism. B-vitamins are required for normal cell growth and neurological function and thus have an impact on human health from the embryo to the older adult. Low folate and/or vitamin B-12 status may yield pregnancy complications, low birth weight, cancer, and cognitive impairment.
The overarching theme of my research is micronutrient adequacy. My current research projects focus on maternal-fetal nutrient dependency, periconceptional vitamin adequacy, and the role of maternal and infant nutrition on growth and development. In the UBC Nutritional Biomarker Laboratory that I established, my team has set up a wide array of externally validated analytical methods. One of our goals is to identify sensitive nutritional biomarkers for early diagnosis of micronutrient inadequacies. With the use of stable isotope tracer protocols, we are able to investigate metabolic and functional consequences of nutritional inadequacies and micronutrient interactions in various population groups. The studies will help elaborate potential underlying mechanisms responsible for linkages between B-vitamin intake and chronic disease risk and in the evaluation of optimal vitamin intake to maintain biochemical functions.
I am interested in supervising graduate students with strong interests in nutritional biochemistry, clinical nutrition, pregnancy and toddler studies, and biomarker analysis. Ideal candidates have strong communication skills for interaction with study participants and have experience or high interest in potential projects with a wet lab component.
The overarching theme of my research is micronutrient adequacy. My current research projects focus on maternal-fetal nutrient dependency, periconceptional vitamin adequacy, and the role of maternal and infant nutrition on growth and development. In the UBC Nutritional Biomarker Laboratory that I established, my team has set up a wide array of externally validated analytical methods. One of our goals is to identify sensitive nutritional biomarkers for early diagnosis of micronutrient inadequacies. With the use of stable isotope tracer protocols, we are able to investigate metabolic and functional consequences of nutritional inadequacies and micronutrient interactions in various population groups. The studies will help elaborate potential underlying mechanisms responsible for linkages between B-vitamin intake and chronic disease risk and in the evaluation of optimal vitamin intake to maintain biochemical functions.
I am interested in supervising graduate students with strong interests in nutritional biochemistry, clinical nutrition, pregnancy and toddler studies, and biomarker analysis. Ideal candidates have strong communication skills for interaction with study participants and have experience or high interest in potential projects with a wet lab component.
研究兴趣
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OPEN BIOLOGYno. 11 (2023): 230217-230217
A Caffrey,Y Lamers, M M Murphy, N Letourneau, R E Irwin,K Pentieva,M Ward, A Tan, A Rojas-Gómez, L A Santos-Calderón, J Canals-Sans,B M Y Leung,
The Journal of nutritionno. 1 (2023): 174-184
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Current Developments in Nutrition (2023): 101082-101082
Current Developments in Nutrition (2023): 101126-101126
Journal of Nutrition (2023)
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
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