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Additionally, our research also extends to the field of structure-based drug design as well as other computational approaches to facilitate drug discovery. Currently, our research is most focused on studying human PFKFB1 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) for diabetes, PFKFB2 for ischemic myocardium, and PFKFB3 for cancer. Additional efforts are being made to DNA (cytosine-5)-methyltransferase for the reprogramming of somatic cells to stem cells by using drug-like small molecule compounds.
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Medical research archivesno. 1 (2022)
Cancer Drug Design and Discoverypp.427-448, (2014)
Jeong-Do Kim,Jong S. Rim, Robert B. Crochet,Yong-Hwan Lee,Jaroslaw Staszkiewicz,Ru Gao,Kenneth J. Eilertsen
CHEMICAL BIOLOGY IN REGENERATIVE MEDICINE: BRIDGING STEM CELLS AND FUTURE THERAPIESpp.163-179, (2014)
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