His major interests focus on physical pharmacy. Specifically, he has designed novel drug delivery systems with further exploration of the underlying mechanisms overcoming the key physiological barriers. He has now published more than 70 peer-reviewed papers in international journals, including Science Advances, Nature Communications, PNAS, Advanced Functional Materials, Advanced Science, ACS Nano, Nano Letters, Biomaterials, Journal of Controlled Release. He has also participated in writing and editing 5 books. In the aspect of translational medicine, Prof. Gan has rationally designed a series of innovative preparations with good druggability, some of which are now undergoing clinical trials. Up to now, he holds 35 authorized patents, 15 clinical approvals for new drugs, and 5 commercial formulations.