基本信息
浏览量:37
职业迁徙
个人简介
The biological world has unparalleled abilities to control structures, functions, reactions, and energy transfer with great efficiency and accuracy. We are interested in biomimetic chemistry to “abstract good design from nature.” One of our main research goals is to design molecules that functionally mimic certain biological systems, and in turn to prepare molecules, polymers, and materials that have useful and superior properties. Our imprinted nanoparticles mimic natural antibodies in their molecular recognition of small-molecule drugs, peptides, and carbohydrates. They serve as excellent supramolecular hosts, specific biomimetic sensors, and smart materials useful for chemistry and biology. Our enzyme-mimetic catalysts carry out highly selective chemical transformations in water under mild conditions. With tunable chiral space near the catalytic center, our synthetic aldolase enables poor chiral (prolinamide) catalysts to achieve up to 99% ee and even racemic catalysts >70% ee.
研究兴趣
论文共 212 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Nature communicationsno. 1 (2024): 3731-3731
JOURNAL OF THE AMERICAN CHEMICAL SOCIETYno. 7 (2024): 4346-4350
JOURNAL OF ORGANIC CHEMISTRYno. 7 (2024): 5148-5152
RSC Chemical Biology (2024)
CATALYSIS SCIENCE & TECHNOLOGYno. 19 (2023): 5702-5709
ORGANIC LETTERSno. 1 (2023): 73-77
bioRxiv (Cold Spring Harbor Laboratory) (2023)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn