基本信息
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职业迁徙
个人简介
1977 University of Chicago, MD。 1975 University of Chicago, PhD, Biochemistry Residency。 1978 - 1979 Boston Children’s Hospital Medical Center, Resident in Pediatrics 1977 - 1978 Boston Children’s Hospital Medical Center, Intern in Pediatrics, Fellowship。 1979 - 1981, Boston Children’s Hospital Medical Center, Fellow in Allergy and Immunology。 1977 - 1979, Harvard Medical School, Clinical Fellow in Pediatrics。
2013 NIAID Immune Tolerance Network, Steering Committee。 2012:NIAID National Allergy and Infectious Disease Advisory Council, Ad hoc member。 2007:NIAID National Allergy and Infectious Disease Advisory Council, Ad hoc Member。 2006: Research Advisory Committee, University of Colorado Denver。 1998: Editor-in-Chief, Journal of Allergy and Clinical Immunology。 1994: Director, NIH Clinical Research Center, National Jewish Health。 1991: Professor, Department of Pediatrics, University of Colorado Denver。 1990-91: Associate Professor, Dept of Pediatrics, University of Colorado Denver。
Awards & Recognition
2012: Named by US News and World Report as among the top 1% of physicians
2012: AAAAI Distinguished Service Award
2012: Sir QW Lecturer, Hong Kong Allergy Convention
2011: Reviewer, NIH/National Heart, Lung and Blood Institute, Special Emphasis Panel for ancillary asthma clinical trials
2009: Arthur Rook Oration at 79th British Assn of Dermatology
2008: Reviewer, The Center for Scientific Review National Institutes of Health, Small Business Innovation Research (SBIR), Small Business Technology Transfer Research (STTR)
2008: NIH/FDA Expert Panel on Food Allergy
2008: Outstanding Scientific Achievement in Clinical Research Award, NJH
2007: Soc of Investigative Dermatology, Julius Stone Lectureship
2007: Chair, Medical Advisory Board, Food Allergy Initiative
2007: NIH/NIAID Res Advisory Council
2006-09: SPR E Mead Johnson Award Selection Comm
2006: ISI Most Highly Cited Authors in Immunology (top half percent of citations in previous 20 years)
2005: Robert Cooke Memorial Lectureship at AAAAI
2004-08: Board of Dir, AAAAI 2004: American Skin Assoc Annual Psoriasis Achievement Award
2004: Edelstein Chair in Pediatric Allergy/Immunology, NJH
2004: Pfizer Visiting Professorship, Univ Chicago
2004: Erich Hoffmann Mem Lecturership, Bonn
2004: 17th James N. Gilliam Mem Lectureship, Univ Texas SW Med Ctr, Dallas
My research focuses on mechanisms by which bacteria and viruses contribute to skin inflammation of atopic dermatitis and psoriasis. I am interested in why patients with atopic dermatitis are prone to microbial infection. As well, I have an interest in mechanisms resulting steroid resistance and the treatment of peanut allergy.
Publications
Irvine AD, McLean WHI, Leung DYM. Filaggrin mutations: Associations with skin and allergic diseases. N Engl J Med 2011; 365(14): 1315-27.
Searing DA, Zhang Y, Murphy JR, Hauk PJ, Goleva E, Leung DY. Decreased serum vitamin D levels in children with asthma are associated with increased corticosteroid usage. J Allergy Clin Immunol 2010; 125:995-1000.
Leung DYM, Gao PS, Grigoryev DN, Rafaels NM, Streib JE, Howell M D, Taylor PA, Boguniewicz M, Canniff J, Armstrong B, Zaccaro DJ, Schneider LC, Hata TR, Hanifin JM, Beck LA,Weinberg A, Barnes KC. Human atopic dermatitis complicated by eczema herpeticum is associated with abnormalities in gamma interferon response. J Allergy Clin Immunol 2011; 127:965-73. PMID: 21458658. PMCID: PMC3074534
Leung DY, Sampson HA, Yunginger JW, Burks AW Jr, Schneider LC, Wortel CH, Davis FM, Hyun JD, Shanahan WR Jr, for the TNX-901 Peanut Allergy Study Group. Effect of anti-IgE therapy (TNX-901) in patients with peanut allergy. N Engl J Med 2003;348:986-93.
Ong PY, Ohtake T, Brandt C, Strickland I, Boguniewicz M, Ganz T, Gallo RL, Leung DY. Endogenous antimicrobial peptides and skin infections in atopic dermatitis. N Engl J Med 2002;347:1151-60.
研究兴趣
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