基本信息
浏览量:5
职业迁徙
个人简介
My roles include assay design and development, functional assays, trouble
shooting, quality control, supervising staff scientists and technicians, communicating with and providing technical assistance to the investigators who requesting screening services from PDSP. Over the years, I have been involved in many collaboration projects, from high throughput screening campaigns to characterization of lead compounds and structure-activity relationship (SAR) studies; from GPCR structure projects to functional selectivity (bias), probe design and optimization. In the same time, I have been developing my own research
projects focusing on H+-sensing GPCRs, also funded by NIMH. I reported the first small molecule positive allosteric modulator (PAM) ogerin, selective for GPR68 and now commercially available from several vendors as a tool compound.
shooting, quality control, supervising staff scientists and technicians, communicating with and providing technical assistance to the investigators who requesting screening services from PDSP. Over the years, I have been involved in many collaboration projects, from high throughput screening campaigns to characterization of lead compounds and structure-activity relationship (SAR) studies; from GPCR structure projects to functional selectivity (bias), probe design and optimization. In the same time, I have been developing my own research
projects focusing on H+-sensing GPCRs, also funded by NIMH. I reported the first small molecule positive allosteric modulator (PAM) ogerin, selective for GPR68 and now commercially available from several vendors as a tool compound.
研究兴趣
论文共 128 篇作者统计合作学者相似作者
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biorxiv(2023)
Madigan L. Bedard, Jackson G. Murray,Xi-Ping Huang,Alexandra C. Nowlan,Sara Y. Conley,Sarah E. Mott, Samuel J. Loyack, Calista A. Cline, Caroline G. Clodfelter,Nabarun Dasgupta,Bryan L. Roth,Zoe A. McElligott
biorxiv(2023)
引用1浏览0引用
1
0
The EMBO Journalno. 11 (2023)
引用5浏览0引用
5
0
Richard T Eastman,Radda Rusinova,Karl F Herold,Xi-Ping Huang,Patricia Dranchak,Ty C Voss, Sandeep Rana,Jonathan H Shrimp, Alex D White,Hugh C Hemmings,Bryan L Roth,James Inglese,
bioRxiv : the preprint server for biology (2023)
biorxiv(2022)
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