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His research focuses on biomedical photonics, and he has specific expertise in fluorescence imaging and spectroscopy, optical coherence tomography (OCT), and multiphoton endomicroscopy for cancer detection, surgical guidance, and preterm-birth risk assessment etc. His research group pioneered the development of the first ultra-compact, fully integrated, single-fiber scanning endomicroscope for performing label-free functional imaging of tissue histology in vivo, in situ, and in real time. The ultimate goal of the research in his team is to transform our capability of disease detection at early, manageable stages, reduction of the (random) sampling errors in clinical diagnosis, monitoring of therapeutic effects and treatment outcomes, and guidance of interventions. The technologies developed in his team also offer new opportunities for basic research in exploring new frontiers of disease mechanisms, brain function, bio-marker discovery, and integrated diagnosis and therapy.
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BME frontiers (2024): 0041-0041
IEEE transactions on bio-medical engineeringno. 99 (2024): 1-7
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII (2024)
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII (2024)
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