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个人简介
Dr. Tetzlaff is currently focused on two distinct areas of research. The first focuses on early strategies that will assist in protecting against secondary damage after SCI, termed neuroprotection. After an injury, there is the possibility of a cascade effect, which involves a chain of secondary injuries. Neuroprotective strategies would work to mitigate further injury by preventing cascade effects. To this end, he is studying dietary strategies, like the ketogenic diet and every-other-day fasting (EODF). His second area of research is focused on repair, since you cannot protect against all injury. To re-connect with other neurons and restore function following injury, nerve fibres must grow across the lesion or injury site. Unfortunately, spinal cord cells are unable to regenerate in this way. Currently, Dr. Tetzlaff is using approaches such as gene manipulation to enhance the regenerative potential of nerve fibers. He is also working on remyelination strategies, which involves the construction of new myelin sheathes to replace those lost from the nerve fibers due to injury. In the brain and spinal cord, myelin helps neurons function more efficiently by wrapping around them and could also protect them from additional damage.
研究兴趣
论文共 292 篇作者统计合作学者相似作者
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Michelle H Lam, Masha Novoselova,Andrew Yung, Valentin H Prevost,Alan P Manning,Jie Liu,Wolfram Tetzlaff,Piotr Kozlowski
S. B. Manesh,B. R. Kondiles, S. Wheeler, J. Liu, L. Zhang, C. Chernoff,G. J. Duncan,M. S. Ramer,W. Tetzlaff
Oscar Seira, HyoJoon (David) Park,Jie Liu, Michelle Poovathukaran,Kieran Clarke,Robert Boushel,Wolfram Tetzlaff
Lucie Bourguignon,Louis P. Lukas, Bethany R. Kondiles,Bobo Tong, Jaimie J. Lee,Tomas Gomes,Wolfram Tetzlaff,John L. K. Kramer,Matthias Walter,Catherine R. Jutzeler
COMMUNICATIONS MEDICINEno. 1 (2024)
Shayan Keymanesh, Kira Tosefsky,Joyce S. T. Lam,Avril Metcalfe‐Roach, Petra Uzelman,Matthew Sacheli,Wolfram Tetzlaff,Tamara Cohen,Cheryl L. Wellington,B. Brett Finlay,Silke Appel‐Cresswell
Research Square (Research Square) (2023)
Association of British Neurologists Annual Meeting Abstracts 2023 (2023)
Ketogenic Diet and Metabolic Therapiespp.198-215, (2022)
B. Kondiles,M. Anwer,W. H. Cheng,J. Fan, J. C. Barron,K. McInnes,H. Cheung, J. Earle,P. Cripton,C. Wellington,W. Tetzlaff
JOURNAL OF NEUROTRAUMAno. 15-16 (2022): A14-A14
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#Papers: 292
#Citation: 20537
H-Index: 74
G-Index: 139
Sociability: 7
Diversity: 3
Activity: 11
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