基本信息
浏览量:281
职业迁徙
个人简介
William R. Jacobs, Jr. is a Professor of Microbiology and Immunology and of Genetics at Albert Einstein College of Medicine (AECOM) and is also an Investigator in the Howard Hughes Medical Institute. As a graduate student with Drs. Josephine E. Clark-Curtiss and Roy Curtiss III at the University of Alabama at Birmingham, he constructed the first genomic libraries of Mycobacterium leprae from bacilli that had been grown in nine-banded armadillos. He then joined the lab of Dr. Barry Bloom at Einstein with the goal of developing gene transfer for the Mycobacterium tuberculosis and the TB vaccine strain, BCG. In a seminal paper published in Nature in 1987, Dr. Jacobs reported the introduction of foreign DNA into mycobacteria for the first time, using a novel mycobacteriophage vector called a shuttle phasmid. These shuttle phasmids were key to developing plasmid transformation, efficient transposon mutagenesis, specialized transduction, and reporter phages for M. tuberculosis. More recently, Dr. Jacobs has been a founding scientist for the Howard sponsored research multiplex, K-RITH (KwaZulu Natual Research Institute on Tuberculosis and HIV) located in Durban, South Africa.
研究兴趣
论文共 201 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
ANTIMICROBIAL AGENTS AND CHEMOTHERAPYno. 1 (2024): e0109623-e0109623
The Journal of clinical investigationno. 19 (2023)
Pathogensno. 1109 (2023): 1109-1109
引用0浏览0WOS引用
0
0
Claire V Mulholland, Thomas J Wiggins, Jinhua Cui,Catherine Vilchèze,Saranathan Rajagopalan,Michael W Shultis, Esmeralda Z Reyes-Fernández,William R Jacobs,Michael Berney
bioRxiv : the preprint server for biology (2023)
ACS Infectious Diseasesno. 4 (2023): 966-978
引用1浏览0引用
1
0
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Shivani Singh, David Kanzin, Sarah Chavez, N Alejandra Saavedra-Avila,Tony W Ng,Regy Lukose, Oren Mayer,John Kim, Bing Chen, Mei Chen,Steven A Porcelli,William R Jacobs,
bioRxiv : the preprint server for biology (2023)
引用0浏览0WOS引用
0
0
Pathogensno. 1330 (2022): 1330-1330
引用0浏览0引用
0
0
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn