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个人简介
I have a long-standing interest in the use of genetic markers to elucidate population structure and breeding behaviour, originally in marine mammals, coupled with studies on how these markers evolve. Since the 1990's I have developed the idea that heterozygous sites attract additional mutations at and around them, creating a link between evolutionary rate and population size. It was testing this hypothesis that led me to the prediction that mutation rate in humans would have dropped as a result of the large loss of variability that occurred during the out of Africa event, and thence to an alternative model to inter-breeding that could explain why non-Africans are closer to Neanderthals than Africans. Work in this area has pre-occupied me for more than a decade but challenging the idea that many humans carry Neanderthal legacies has proved near-impossible! Below is a document summarising many of my ideas, analyses and reasons why these legacies appear to be near-zero. To make this as self-contained and easy to share as possible, I start with a very brief bio.
研究兴趣
论文共 237 篇作者统计合作学者相似作者
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BEHAVIORAL ECOLOGYno. 6 (2023): 950-959
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Shannan Foylan,William Bradshaw Amos,John Dempster, Lisa Koelln, Carsten G. Hansen,Michael J. Shaw,Gail McConnell
Single Molecule Spectroscopy and Superresolution Imaging XVI (2023)
SINGLE MOLECULE SPECTROSCOPY AND SUPERRESOLUTION IMAGING XVI (2023)
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Liam M Rooney, Jay Christopher, Ben Watson, Yash Susir Kumar, Laura Copeland,Lewis D Walker,Shannan Foylan,William Bradshaw Amos,Ralf Bauer,Gail McConnell
biorxiv(2023)
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biorxiv(2022)
Genetics and the Extinction of Speciespp.75-100, (2021)
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