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Dr. Web Cavenee has fundamentally changed the way scientists now think about the onset of cancer and its progression. He provided the first indisputable evidence of the existence of tumor suppressor genes.
Dr. Cavenee’s original research sought to define the genetic lesions in retinoblastoma and led to evidence that there’s tumor suppression in humans. Today, mutations of tumor suppressor genes have been identified in more than half of all tumors, including those of muscle, melanocytes, kidney, prostate and breast. Gene therapies are being tested that would reverse gene mutations (or their effects) in cancer cells. These therapies hold tremendous promise for patients with brain tumors and many other cancers.
Dr. Cavenee’s original research sought to define the genetic lesions in retinoblastoma and led to evidence that there’s tumor suppression in humans. Today, mutations of tumor suppressor genes have been identified in more than half of all tumors, including those of muscle, melanocytes, kidney, prostate and breast. Gene therapies are being tested that would reverse gene mutations (or their effects) in cancer cells. These therapies hold tremendous promise for patients with brain tumors and many other cancers.
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论文共 623 篇作者统计合作学者相似作者
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Mio Harachi,Kenta Masui, Erika Shimizu, Kumiko Murakami,Hiromi Onizuka,Yoshihiro Muragaki,Takakazu Kawamata,Hisako Nakayama,Mariko Miyata,Takashi Komori,Webster K. Cavenee,Paul S. Mischel,
Acta Neuropathologica Communicationsno. 1 (2024): 1-17
Jill Wykosky,Jingjing Hu,German G. Gomez,Tiffany Taylor, Genaro R. Villa,Donald Pizzo,Scott R. VandenBerg, Amy Haseley Thorne,Clark C. Chen,Paul S. Mischel,Steven L. Gonias,Webster K. Cavenee,
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Jill Wykosky,Jingjing Hu,German G. Gomez,Tiffany Taylor, Genaro R. Villa,Donald Pizzo,Scott R. VandenBerg, Amy Haseley Thorne,Clark C. Chen,Paul S. Mischel,Steven L. Gonias,Webster K. Cavenee,
crossref(2023)
Jill Wykosky,Jingjing Hu,German G. Gomez,Tiffany Taylor, Genaro R. Villa,Donald Pizzo,Scott R. VandenBerg, Amy Haseley Thorne,Clark C. Chen,Paul S. Mischel,Steven L. Gonias,Webster K. Cavenee,
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Kazuhiro Tanaka,Ivan Babic,David Nathanson,David Akhavan,Deliang Guo,Beatrice Gini,Julie Dang,Shaojun Zhu,Huijun Yang, Jason De Jesus, Ali Nael Amzajerdi,Yinan Zhang,
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Kan V. Lu,Shaojun Zhu,Anna Cvrljevic,Tiffany T. Huang,Shawn Sarkaria, David Ahkavan,Julie Dang,Eduard B. Dinca, Seema B. Plaisier, Isaac Oderberg,Yohan Lee,Zugen Chen,
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