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Dr. Wei Dong Gao is an associate professor of anesthesiology and critical care medicine at the Johns Hopkins University School of Medicine. His areas of clinical expertise include anesthesiology.
Dr. Gao earned his M.D. from Harbin Medical University in China and his Ph.D. from the University of Calgary. He completed post-doctoral training at Johns Hopkins. He performed his residencies at University Hospital in Cincinnati, Ohio, and a fellowship in cardiac anesthesia at Johns Hopkins. Dr. Gao joined the Department of Anesthesiology and Critical Care Medicine at Johns Hopkins in 2002.
Prior to joining Johns Hopkins, Dr. Gao was a research assistant in the Department of Medicine and Medical Physiology at the University of Calgary. He was a research associate in the molecular and cellular cardiology section in the Department of Medicine at Johns Hopkins from 1995 to 1997.
Dr. Gao’s work was recognized by Johns Hopkins with a Clinician Scientist Award from 2002 to 2004. He is a member of several professional organizations, including the Association of University Anesthesiologists and the American Society of Anesthesiology.
The main goal of Dr. Wei Dong Gao’s research is to define the molecular and cellular mechanisms of contractile dysfunction in the failing heart. To work toward this goal, he is using a variety of state-of-the-art techniques. Using the fluorescent dye fura-2 salt, he measures the intracellular free calcium concentration in a multicellular cardiac tissue preparations called trabeculae. In the same preparations, he measures sarcomere length (using a laser diffraction technique) and force development simultaneously. In addition, he uses molecular biology and proteomic techniques to investigate the changes that myofilament proteins undergo during heart failure and under drug therapy. Dr. Gao’s current focus is determining the molecular nature of nitroxyl (HNO) modification of tropomyosin. He is also planning to study the physiology and biochemistry of atrial tissue and muscle during atrial fibrillation and/or atrial failure and the effect of atrial dysfunction on the development and progress of heart failure. In the future he hopes to characterize endo-myocardio-coupling in failing heart. He would like to investigate the role of endothelial endocardium, the role of coronary endocardium, and the effects of agents released from endothelial cells.
Dr. Gao earned his M.D. from Harbin Medical University in China and his Ph.D. from the University of Calgary. He completed post-doctoral training at Johns Hopkins. He performed his residencies at University Hospital in Cincinnati, Ohio, and a fellowship in cardiac anesthesia at Johns Hopkins. Dr. Gao joined the Department of Anesthesiology and Critical Care Medicine at Johns Hopkins in 2002.
Prior to joining Johns Hopkins, Dr. Gao was a research assistant in the Department of Medicine and Medical Physiology at the University of Calgary. He was a research associate in the molecular and cellular cardiology section in the Department of Medicine at Johns Hopkins from 1995 to 1997.
Dr. Gao’s work was recognized by Johns Hopkins with a Clinician Scientist Award from 2002 to 2004. He is a member of several professional organizations, including the Association of University Anesthesiologists and the American Society of Anesthesiology.
The main goal of Dr. Wei Dong Gao’s research is to define the molecular and cellular mechanisms of contractile dysfunction in the failing heart. To work toward this goal, he is using a variety of state-of-the-art techniques. Using the fluorescent dye fura-2 salt, he measures the intracellular free calcium concentration in a multicellular cardiac tissue preparations called trabeculae. In the same preparations, he measures sarcomere length (using a laser diffraction technique) and force development simultaneously. In addition, he uses molecular biology and proteomic techniques to investigate the changes that myofilament proteins undergo during heart failure and under drug therapy. Dr. Gao’s current focus is determining the molecular nature of nitroxyl (HNO) modification of tropomyosin. He is also planning to study the physiology and biochemistry of atrial tissue and muscle during atrial fibrillation and/or atrial failure and the effect of atrial dysfunction on the development and progress of heart failure. In the future he hopes to characterize endo-myocardio-coupling in failing heart. He would like to investigate the role of endothelial endocardium, the role of coronary endocardium, and the effects of agents released from endothelial cells.
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JOURNAL OF CLINICAL ANESTHESIA (2024): 111409-111409
Xiaojun He,Qiang Long,Yiming Zhong, Zhaoxi Qi,Yecen Zhang,Bei Qian,Shixing Huang,Xinming Wang,Xiaomei Yang,Wei Dong Gao, Xiaofeng Ye,Qiang Zhao
crossref(2024)
Joseph Walpole,Wei Dong Gao
Current Anesthesiology Reportsno. 4 (2023): 213-218
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