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个人简介
Dr. Figg is an expert in molecular and clinical pharmacology, and utilizing pharmacological principles in anticancer drug and biomarker development. His research spans the entire drug development pipeline from target identification/validation in drug discovery to preclinical development and ultimately clinical evaluation. Dr. Figg’s main research interest lies in the development of novel anticancer agents. His laboratory is focused on 1) understanding the genetics and molecular mechanisms that drive prostate cancer progression; 2) elucidating mechanisms responsible for cancer drug resistance to develop novel treatment strategies for patients with advanced prostate cancer and other metastatic processes who have progressed on standard regimens; and 3) developing bench-to-bedside-to-bench approaches to facilitate the identification of novel druggable targets and for assessment of pharmacokinetics, pharmacodynamic, and pharmacogenetics biomarkers in monitoring clinical response and resistance to therapy.
Dr. Figg also oversees the Clinical Pharmacology Program within the Office of Clinical Director, which provides comprehensive clinical pharmacology assessment of new anticancer agents and comprises of four unique sections: Biospecimen Processing Core, Pharmacokinetics and Pharmacometrics Section (which includes the Bioanalytical Unit and Preclinical Pharmacology Unit), Pharmacogenetics Section, and Clinical Section.
Dr. Figg also co-chairs (with Dr. Pat Steeg) the Office of Translational Resources.
Areas of Expertise
1) molecular/clinical pharmacology 2) drug development 3) prostate cancer 4) pharmacogenetics/pharmacogenomics 5) angiogenesis 6) biomarker development
研究兴趣
论文共 1011 篇作者统计合作学者相似作者
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TRANSLATIONAL CANCER RESEARCHno. 1 (2024): 11-14
Journal of Racial and Ethnic Health Disparitiesno. 1 (2024): 492-504
JOURNAL FOR IMMUNOTHERAPY OF CANCERno. 1 (2024)
Transplantation and Cellular Therapyno. 2 (2023): S251-S252
European urology oncology (2023)
Journal of Clinical Oncologyno. 6_suppl (2023): 141-141
Jerry T. Wu,Adam Cheuk, Kristine Isanogle,Christina Robinson,Xiaohu Zhang,Michele Ceribelli,Erin Beck,Paul Shinn,Carleen Klumpp-Thomas,Kelli M. Wilson,Crystal Mcknight,Zina Itkin,
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA (2023): S424-S425
Yilun Sun,Simone A. Baechler,Xiaohu Zhang,Suresh Kumar,Valentina M. Factor, Yasuhiro Arakawa,Cindy H. Chau, Kanako Okamoto,Anup Parikh, Bob Walker,Yijun P. Su,Jiji Chen,
Nature Communicationsno. 1 (2023): 1-20
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