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个人简介
Firstly he used his expertise in gene targeting in the mouse to study signal transduction in lymphocytes, exploring the roles of signaling molecules such as Syk, Vav1, Rac1 and Rac2 in B and T cell development, activation and survival.
Secondly, in close collaboration with Elizabeth Fisher, he used his knowledge of genetic manipulation of mice to generate a novel model of Down Syndrome, the Tc1 mouse strain. This strain of mice carries a freely segregating copy of human chromosome 21 and has a number of phenotypes resembling the human condition, including defects in learning and memory, cardiac and craniofacial defects.
Secondly, in close collaboration with Elizabeth Fisher, he used his knowledge of genetic manipulation of mice to generate a novel model of Down Syndrome, the Tc1 mouse strain. This strain of mice carries a freely segregating copy of human chromosome 21 and has a number of phenotypes resembling the human condition, including defects in learning and memory, cardiac and craniofacial defects.
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论文共 296 篇作者统计合作学者相似作者
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Eva Lana-Elola,Rifdat Aoidi,Miriam Llorian,Dorota Gibbins, Callan Buechsenschuetz,Claudio Bussi,Helen Flynn, Tegan Gilmore,Sheona Watson-Scales, Marie Haugsten Hansen, Darryl Hayward, Ok-Ryul Song,
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DISEASE MODELS & MECHANISMSno. 4 (2023)
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Leonard L. de Boer,Lesley Vanes,Serena Melgrati, Joshua Biggs O’May,Darryl Hayward,Paul C. Driscoll,Jason Day, Alexander Griffiths, Renata Magueta,Alexander Morrell,James I. MacRae,Robert Köchl,
biorxiv(2023)
Kourtney Sloan,Jared Thomas,Matthew Blackwell, Deanna Voisard,Eva Lana-Elola,Sheona Watson-Scales, Daniel L Roper,Joseph M Wallace,Elizabeth M C Fisher,Victor L J Tybulewicz,Randall J Roper
Maria Elisa Serrano,Eugene Kim,Bernard Siow,Da Ma, Loreto Rojo,Camilla Simmons,Darryl Hayward,Dorota Gibbins,Nisha Singh,Andre Strydom, Elizabeth M. C. Fisher,Victor L. J. Tybulewicz,
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Joseph L. Kissil, Marita J. Walmsley, Linda Hanlon,Kevin M. Haigis,Carla F. Bender Kim,Alejandro Sweet-Cordero, Matthew S. Eckman,David A. Tuveson,Anthony J. Capobianco,Victor L.J. Tybulewicz,Tyler Jacks
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Joseph L. Kissil, Marita J. Walmsley, Linda Hanlon,Kevin M. Haigis,Carla F. Bender Kim,Alejandro Sweet-Cordero, Matthew S. Eckman,David A. Tuveson,Anthony J. Capobianco,Victor L.J. Tybulewicz,Tyler Jacks
crossref(2023)
Phillip M. Muza, Marta Pérez,Suzanna Noy, Miyu Kurosawa,Loukia Katsouri,Victor L. J. Tybulewicz, Elizabeth M.C. Fisher,Steven J. West
BMC research notesno. 1 (2023): 246-7
Eva Lana-Elola,Rifdat Aoidi,Miriam Llorian,Dorota Gibbins, Callan Buechsenschuetz,Claudio Bussi,Helen Flynn, Tegan Gilmore,Sheona Watson-Scales, Marie Haugsten Hansen,Darryl Hayward,Ok-Ryul Song,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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