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The tumor initiation, progression and clinical presentation are directly dependent on its genetic and biochemical environment – the entire body. Our group is working on different projects related to how genetic variation affects occurrence of somatic alterations, gene expression patterns and genome wide copy number alterations in human breast and ovarian tumors. Understanding inherited genetic variability and how it affects crucial biological pathways is likely to lead to new successful prevention and treatment strategies.
The research in the group is focusing on constitutive variation such as single nucleotide polymorphisms (SNPs) and copy number variations (CNVs) in relation to:
Susceptibility
Clinical presentation
Treatment response and adverse side effects of treatment
Gene regulation and proximal phenotypes (RNA expression and metabolic profiles)
The research in the group is focusing on constitutive variation such as single nucleotide polymorphisms (SNPs) and copy number variations (CNVs) in relation to:
Susceptibility
Clinical presentation
Treatment response and adverse side effects of treatment
Gene regulation and proximal phenotypes (RNA expression and metabolic profiles)
研究兴趣
论文共 402 篇作者统计合作学者相似作者
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Vessela N. Kristensen, Grethe I. Alnaes, Patrik Vernhoff, Leonard Schmiester, Salim Ghannoum, Marie Fongaard, Paal M. Bjornstad, Knut Selsaas,Stephanie Geisler,Manouchehr Seyedzadeh,Unn-Cathrin Buvarp,Torben Luders,
Cancer Researchno. 7_Supplement (2024)
Mari Tinholt,Xavier Tekpli, Lilly Anne Torland,Andliena Tahiri,Jürgen Geisler,Vessela Kristensen,Per Morten Sandset,Nina Iversen
Journal of thrombosis and haemostasis : JTH (2024)
Gemma Santacana-Font, Darek Kedra, Maria del Carmen García-Macías, Laurens Cornelus-Reitsma,Marianne Lyngra,Torill Sauer,Vessela Kristensen,Antoni Hurtado,Jürgen Geisler
Cancer Researchno. 6_Supplement (2024): 7576-7576
Bulletin of Mathematical Biologyno. 4 (2024): 1-33
Maria Zanti, Denise G. O'Mahony,Michael T. Parsons,Hongyan Li,Joe Dennis, Kristiina Aittomakkiki,Irene L. Andrulis,Hoda Anton-Culver,Kristan J. Aronson,Annelie Augustinsson,Heiko Becher,Stig E. Bojesen,
Jo Anders Rønneberg,Jörg Tost,Hiroko K. Solvang,Grethe I.G. Alnaes, Fredrik E. Johansen, Elen M. Brendeford,Zohar Yakhini,Ivo G. Gut,Per Eystein Lønning,Anne-Lise Børresen-Dale,Odd S. Gabrielsen,Vessela N. Kristensen
crossref(2023)
Jo Anders Rønneberg,Jörg Tost,Hiroko K. Solvang,Grethe I.G. Alnaes, Fredrik E. Johansen, Elen M. Brendeford,Zohar Yakhini,Ivo G. Gut,Per Eystein Lønning,Anne-Lise Børresen-Dale,Odd S. Gabrielsen,Vessela N. Kristensen
crossref(2023)
Cancer Researchno. 5_Supplement (2023): OT2-19
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