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Professor Vance L. Trudeau holds the University of Ottawa Research Chair in Neuroendocrinology and leads a team of dynamic graduate students with wide interests. His group's research is directed towards understanding how the vertebrate brain regulates anterior pituitary hormones that control sexual development and reproduction using fish and frog models. Applications of this basic research include spawning induction methods for endangered amphibians, among others. One of the most compelling recent discoveries is the fundamental role of a peptide called secretoneurin. Based on work in goldfish, zebrafish and mice, we have made the proposal that it is a new reproductive hormone. The team also studies the effects of sex steroids and pollutants (pharmaceuticals, pesticides, petroleum products) on development and reproduction in fish and frogs. This concept is called endocrine disruption. This has important implications for environmental and human health because many of these hormonal systems are conserved across species. This means that what is discovered in one species, has major implications in other vertebrate, including humans.
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Vance L. Trudeau, Gustavo M. Somoza
Reference Module in Biomedical Sciencespp.560-566, (2024)
Elsevier eBookspp.1-13, (2023)
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Chunyu Lu, Di Peng, W C K Udeesha Erandani,Kimberly Mitchell,Christopher J Martyniuk,Vance L Trudeau
Frontiers in endocrinology (2023): 1266985
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Frontiers in Endocrinology (2023): 1308675-1308675
Frontiers in endocrinology (2023): 1225199
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