His papers are highly cited (h-index: 47) and his group significantly contributed to the paradigm shift that not only targeted effects of radiation on the DNA do exist, but also systemic and immune-mediated ones. The research focuses on immune modulation by activated, stressed and dying tumor cells, on radiation-induced stimulators and suppressor of the innate and adaptive immune system, on osteoimmunological modes of action of low radiation doses, on radioimmunotherapies, hyperthermia and immunophenotyping, as well as on translational clinical studies. He was WP leader of several EU funded projects and currently is key scientist and deputy head of a German research network dealing with the influence of exposure to low doses of radiation on the innate and adaptive immune system. Further he is commissioner and project leader of the DFG-Graduate School 1660 on Key Signals of Adaptive immune Responses and he heads a consortium funded by the Bayerische Forschungsstiftung on Multiscale Investigations of Hyperthermia as Additive Treatment Strategy for Solid Tumors.