基本信息
浏览量:149
职业迁徙
个人简介
Research Area: Cell and Molecular Biology
Research Description:
Our group analyzes the functional organization of the nucleus. Components of the nuclear envelope and the nuclear transport apparatus are implicated in human disease, including several types of cancer. For our studies, mammalian-cultured cells and the budding yeast Saccharomyces cerevisiae serve as model systems.
We are particularly interested in nuclear envelope proteins and their role in organizing chromatin. In addition, trafficking of macromolecules in and out of the nucleus is being analyzed. These transport processes control cellular metabolism and are essential for cell survival upon stress. We are presently defining how different forms of stress affect trafficking between nucleus and cytoplasm. These questions are addressed with a combination of genetics, biochemistry, cell and molecular biology.
Research Description:
Our group analyzes the functional organization of the nucleus. Components of the nuclear envelope and the nuclear transport apparatus are implicated in human disease, including several types of cancer. For our studies, mammalian-cultured cells and the budding yeast Saccharomyces cerevisiae serve as model systems.
We are particularly interested in nuclear envelope proteins and their role in organizing chromatin. In addition, trafficking of macromolecules in and out of the nucleus is being analyzed. These transport processes control cellular metabolism and are essential for cell survival upon stress. We are presently defining how different forms of stress affect trafficking between nucleus and cytoplasm. These questions are addressed with a combination of genetics, biochemistry, cell and molecular biology.
研究兴趣
论文共 109 篇作者统计合作学者相似作者
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BIOCHEMISTRY AND CELL BIOLOGYno. 2 (2024): 206-212
Kais Bietar,Siwei Chu,Gabrielle Mandl, Emma Zhang, Naim Chabaytah, Renata Sabelli,John A. Capobianco,Ursula Stochaj
RSC ADVANCESno. 13 (2024): 8695-8708
Cellsno. 11 (2024)
Kais Bietar,Siwei Chu,Gabrielle Mandl, Emma Zhang, Naim Chabaytah, Renata Sabelli,John A. Capobianco,Ursula Stochaj
RSC Advancesno. 13 (2024): 8695-8708
EUROPEAN JOURNAL OF CELL BIOLOGYno. 1 (2024): 151376-151376
Aspects of Molecular Medicine (2023): 100021-100021
引用1浏览0引用
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Molecular neurodegenerationno. 1 (2023): 1-34
引用0浏览0WOS引用
0
0
ACS applied bio materialsno. 6 (2023): 2370-2383
Rose Triantafillia Psaroudis,Urvashi Singh,Maximilien Lora,Peter Jeon, Abigail Boursiquot,Ursula Stochaj,David Langlais,Inés Colmegna
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