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Research interests
The research in Wong group focuses on applying advanced protein engineering technique, specifically directed evolution, to tailor the properties of enzymes for industrial and pharmaceutical applications as well as to elucidate the design principles used by Nature. There are three key areas that we are currently working on: 1) Development of novel molecular biology tools to advance the field of directed evolution (e.g., method to create high quality mutant library), 2) Application of directed evolution to improve existing properties of industrially relevant enzymes (e.g., cytochrome P450s, carbonyl reductases, aromatic peroxygenases and hydrolases) or to create novel functions, and 3) Development of computational tools to facilitate/expedite experimental design (e.g., method to analyse genetic diversity). One of our current research projects is to develop biological carbon dioxide capture and utilization (CCU) strategies for bulk, fine and specialty chemical syntheses, capitalizing on our interest in directed evolution and synthetic biology.
研究兴趣
论文共 70 篇作者统计合作学者相似作者
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Valériane Malika Keita,Yi Qing Lee,Meiyappan Lakshmanan,Dave Siak-Wei Ow,Paul Staniland,Jessica Staniland, Ian Savill,Kang Lan Tee,Tuck Seng Wong,Dong-Yup Lee
Microbial Cell Factoriesno. 1 (2024): 1-17
SynBiono. 2 (2024): 142-173
Springer eBookspp.203-212, (2023)
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Open Access Governmentno. 1 (2023): 244-245
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Springer eBookspp.43-66, (2023)
Open Access Governmentno. 1 (2023): 422-423
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Springer eBooks (2023)
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