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个人简介
His research revolutionised the understanding of signal transduction, the molecular mechanisms by which cells respond to external cues, and how they communicate with each other. He identified the phosphotyrosine-binding Src homology 2 (SH2 domain) as the prototypic non-catalytic interaction module. SH2 domains serve as a model for a large family of protein modules that act together to control many aspects of cellular signalling. Since the discovery of SH2 domains, hundreds of different modules have been identified in many proteins.
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crossref(2023)
bioRxiv (Cold Spring Harbor Laboratory) (2020)
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Paul M. Müller,Juliane Rademacher,Richard D. Bagshaw,Celina Wortmann, Carolin Barth,Jakobus van Unen,Keziban M. Alp,Girolamo Giudice,Rebecca L. Eccles,Louise E. Heinrich,Patricia Pascual-Vargas, Marta Sanchez-Castro,
Paul M. Müller,Juliane Rademacher,Richard D. Bagshaw,Keziban M. Alp,Girolamo Giudice,Louise E. Heinrich, Carolin Barth,Rebecca L. Eccles, Marta Sanchez-Castro,Lennart Brandenburg, Geraldine Mbamalu,Monika Tucholska,
biorxiv(2018)
P.M. Müller, J. Rademacher, R.D. Bagshaw, K.M. Alp,G. Giudice, L.E. Heinrich, C. Barth,R.L. Eccles, M. Sanchez-Castro, L. Brandenburg, G. Mbamalu,Monika Tucholska,
Fabian A Renschler, Susanne R Bruekner, Paulin L Salomon,Amrita Mukherjee,Lars Kullmann,Mira C Schütz-Stoffregen,Christine Henzler,Tony Pawson,Michael P Krahn,Silke Wiesner
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