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Dr. Tokarz's research focuses on microbial discovery and the epidemiology of human infectious diseases. His primary interests center on investigating ticks and tick-borne pathogens and understanding their impact on human disease. Dr. Tokarz's work in the field of tick-borne diseases has been driven by three main hypotheses: i) co-infections with human pathogens are common in ticks and result in human polymicrobial infections; ii) these polymicrobial infections can exacerbate tick-borne disease symptoms; and iii) infections with uncharacterized agents contribute to a proportion of undiagnosed tick-transmitted infections. In an effort to study these paradigms, Dr. Tokarz performs annual tick collections to monitor the prevalence of tick-borne agents. He has developed and implemented molecular and serologic tests that improved diagnosis of patients with tick-borne diseases. He has also analyzed the microbiome of ticks and identified a wide range of new tick-associated agents, including over 30 new viruses. Dr. Tokarz' other interests include pathogen discovery in respiratory disease. He has performed analyses of specimens originating from respiratory disease outbreaks in Asia, Africa, Europe, South and North America. Dr. Tokarz has identified new respiratory viruses, including the the first defined cluster of enterovirus D68, an emerging agent implicated in a severe outbreak of pediatric respiratory disease in the US in 2014.
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PATHOGENSno. 11 (2023): 1371
Matthew J. Cummings,Barnabas Bakamutumaho,Komal Jain,Adam Price,Nicholas Owor,John Kayiwa,Joyce Namulondo,Timothy Byaruhanga,Moses Muwanga,Christopher Nsereko, Irene Nayiga, Stephen Kyebambe,
JAIDS Journal of Acquired Immune Deficiency Syndromes (2023)
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Journal of medical virologyno. 8 (2023)
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AIDS (London, England)no. 2 (2022): 233-245
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