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Dr. Ting Kai (T. K.) Li was appointed to the position of the Director of the National Institute on Alcohol Abuse and Alcoholism (NIAAA) in November 2002. The NIAAA is a component of the National Institutes of Health (NIH) within the U.S. Department of Health and Human Services.
Throughout his distinguished research career, Dr. Li has been at the center of advances that have transformed both the way alcoholism is understood and the means of investigating alcohol's effects on the body and brain. A major focus of Dr. Li's research has been to characterize the structure and dynamics of the multiple genetic variants of alcohol dehydrogenase (ADH), the enzyme that catalyzes the first step in the metabolism of ethanol and the differences among individuals in the physiology of these enzymes. Dr. Li also pioneered the development of animal models in which marked differences in the level of voluntary alcohol consumption could be observed, paralleling the same inborn variation seen in human behavior. The development of these animal lines helped cement the once radical notion that alcohol consumption behavior was genetically influenced.
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Vijay A. Ramchandani,Patricia W. Slattum,Ashwin A. Patkar,Li-Tzy Wu,Jonathan C. Lee, Maitreyee Mohanty,Marion Coe,Ting-Kai Li
SUBSTANCE USE AND OLDER PEOPLEpp.149-170, (2015)
Substance Use and Older Peoplepp.364-371, (2015)
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